The following list contains all superheroes that were seen or mentioned in Mighty Med.
Seen
- Absolute Zero: First appeared in All That Kaz.
- Alley Cat: First appeared in Night of the Living Nightmare.
- Amicus and Harold: First appear in Are You Afraid of the Shark?.
- Blue Tornado: First appeared in Saving the People Who Save People.
- Brain Matter: First appeared in Frighty Med.
- Bubble Man: First appeared in There's a Storm Coming.
- Caduceo: First appeared in Saving the People Who Save People.
- Captain Atomic: First appeared in Atomic Blast From the Past.
- Citadel: First appeared in Sm'oliver's Travels.
- The Crusher: First appeared in Saving the People Who Save People.
- Dark Warrior: First appeared in Two Writers Make a Wrong.
- Disgusto: First appeared in Stop Bugging Me.
- Dynamo: First mentioned in There's a Storm Coming, and first appeared in Future Tense.
- Gamma Girl: First appeared in The Pen Is Mighty Med-ier Than the Sword.
- Gravitas: First appeared in Less Than Hero.
- Gray Granite: First appeared in Evil Gus.
- The Great Defender: First appeared in Pranks for Nothing.
- Incognito: First appeared in Saving the People Who Save People.
- The Human Blade: first appeared in Future Tense.
- Hummingbird: first mentioned in There's a Storm Coming, and later seen in a photo in Mighty Mole.
- Lady Spectrum: First appeared in Less Than Hero.
- Mesmera, first appeared in I, Normo.
- Mr. Quick, first appeared in Growing Pains.
- NeoCortex, first appeared in All That Kaz.
- Optimo, first mentioned in Atomic Blast From the Past, and first appeared in Free Wi-Fi. Known for being Alan's father and Horace's brother-in-law.
- Owl Girl, first appeared in Growing Pains.
- Queen Hornet: First appeared in Stop Bugging Me.
- Remix, first appeared in Guitar Superhero.
- Replikate: First appeared in Stop Bugging Me.
- Scarlet Ace, first mentioned in There's a Storm Coming, and first appeared in Future Tense.
- The Scarlet Cyclone, first appeared in Atomic Blast From the Past.
- The Skipper: First appeared in Less Than Hero.
- Solar Flare I: First appeared in Saving the People Who Save People.
- Solar Flare II: First appeared in Atomic Blast From the Past.
- Snowstorm: First appeared in All That Kaz.
- Spotlight: First appeared in Fantasy League of Superheroes.
- Surge: First appeared in Lockdown.
- Tecton: First appeared in Saving the People Who Save People.
- Timeline: First appeared in It's Not the End of the World.
- Titanio: First appeared in I, Normo.
- Thermometer Man: First appeared in Less Than Hero.
- Valkira: First appeared in The Pen Is Mighty Med-ier Than the Sword.
Mentioned
- Alpha Dog, first mentioned in There's a Storm Coming.
- Black Widower, first mentioned in Storm's End.
- Blurry Girl, first mentioned in Fantasy League of Superheroes.
- Captain Freedom, first mentioned in There's a Storm Coming.
- Captain Infinity, first mentioned in There's a Storm Coming.
- Captain Liberty, first mentioned in There's a Storm Coming.
- Electro Man, first mentioned in There's a Storm Coming.
- Freeze Frame, first mentioned in Saving the People Who Save People.
- Fuse, first mentioned in There's a Storm Coming.
- Gargantuan, first mentioned in Alan's Reign of Terror.
- Geode, first mentioned in There's a Storm Coming.
- High Roller, first mentioned in Mighty Mole.
- Hummingbird, first mentioned in There's a Storm Coming.
- The Icicle, first mentioned in Fantasy League of Superheroes.
- Pencilman, first mentioned in Fantasy League of Superheroes.
- The Pinnacle, first mentioned in There's a Storm Coming.
- Reflexor
- Rewind, first mentioned in How the Mighty Med Have Fallen.
- Silver Shield, first mentioned in Lair, Lair.
- Sitting Duck, first mentioned in Fantasy League of Superheroes.
- Solaris, first mentioned in There's a Storm Coming.
- Spark Plug, first mentioned in Mighty Mole.
- Stratosphere , first mentioned in There's a Storm Coming.
- Syphonix: First mentioned in All That Kaz.
- Two-Headed Man, first mentioned in Two Writers Make a Wrong.
- The Worm, first mentioned in There's a Storm Coming.
- Vanguard, first mentioned in There's a Storm Coming.
Possible Superheroes
- Commodore Chaos
- Galactic Girl
- The Immobilizer
- Jack Dynamite
- Mr. Ultimate
- Numero Uno
- Tactic
Former Superheroes
- The Crusher-Still on call, but has been retired since marriage.
- Experion- Went evil at one point, served the Annihilator for some time.
- Hapax the Elder- Went into exile after his student became The Annihilator. He resides on Caldera, the volcanic world.
- Skylar Storm- Superhero status revoked since turning evil and serving The Annihilator.
Total Superheroes
So far, there have been 60 superheroes in Mighty Med